BDBM50380148 CHEMBL2011156::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 6
SMILES NS(=O)(=O)c1ccc(cc1)C(=O)CSc1ncccn1
InChI Key InChIKey=GQFCFNQXNFZIFC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50380148
Affinity DataKoff: 3.30E+6s-1pH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant at pH 8 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 3.20E+6s-1Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 9.20E+5s-1pH: 6.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKoff: 2.30E+6s-1pH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as association rate constant at pH 7 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 38nMpH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 8 by surface pl...More data for this Ligand-Target Pair
Affinity DataKd: 110nMpH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 8 by surface pla...More data for this Ligand-Target Pair
Affinity DataKon: 0.290M-1s-1pH: 6.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 330nMpH: 6.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 6 by surface pl...More data for this Ligand-Target Pair
Affinity DataKd: 330nMpH: 6.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 6 by surface pla...More data for this Ligand-Target Pair
Affinity DataKon: 0.140M-1s-1pH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant at pH 7 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 62nMpH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from kinetic parameters at pH 7 by surface pl...More data for this Ligand-Target Pair
Affinity DataKd: 80nMpH: 7.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation constant calculated from saturation signal at pH 7 by surface pla...More data for this Ligand-Target Pair
Affinity DataKon: 0.120M-1s-1pH: 8.0Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant at pH 8 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.210M-1s-1Assay Description:Binding affinity to human recombinant CA9 catalytic domain assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 66nMAssay Description:Binding affinity to human recombinant CA9 catalytic domain after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 83nMAssay Description:Binding affinity to human recombinant CA9 catalytic domain by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.130nMAssay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as intrinsic thermodynamic equilibrium constant at p...More data for this Ligand-Target Pair
Affinity DataKon: 0.210M-1s-1Assay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair